Journal of Experimental Hematology 2006;14(4):840-844

Progress on the research of microRNA and its functions in lymphoid malignancies--review.

Wei XU 1 ; Jian-Yong LI ; Feng-Xiang LU

Affiliations

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Country

China

Language

Chinese

Abstract

Plant and animal genomes contain an abundance of small genes that produce RNAs of about 22 nucleotides in length, which was dubbed as microRNA (miRNA). These newly found endogenous RNAs may participate in a wide range of genetic regulatory pathways and play an important role in the organism development. This paper reviewed the recent studies and progress on the characteristics, functions and mechanisms of the microRNAs, as well as the advances of research on lymphoid malignancies.