Acta Pharmaceutica Sinica 2009;44(2):154-157

Xanthones from leaves of Calophyllum inophyllum Linn.

Yuan LI 1 ; Zhan-Lin LI ; Ming-Sheng LIU ; Dan-Yi LI ; Hui ZHANG ; Hui-Ming HUA

Affiliations

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Country

China

Language

Chinese

Abstract

To study the xanthones from the leaves of Calophyllum inophyllum Linn., several chromatography methods were employed to isolate the constituents. Investigation on the CHCl3 extract led to the isolation of a new xanthone named inophyxanthone A (1) and four known compounds, which were pancixanthone A (2), gerontoxanthone B (3), jacareubin (4) and pyranojacareubin (5). Among them, compound 2 was obtained from this plant firstly, and compound 3 was obtained for the first time from this genus. The structure of inophyxanthone A (1) was identified as 1, 3, 5-trihydroxy-2-(1, 1-dimethylallyl)xanthone by spectral analysis.