International Journal of Stem Cells  2013;6(2):87-91

Biomimetic Polymer Scaffolds to Promote Stem Cell-Mediated Osteogenesis.

Eunkyung KO 1 ; Seung Woo CHO

Affiliations

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Keywords

Bone tissue engineering; Biomimetic scaffolds; Stem cells; Osteoinductivity

Country

Republic of Korea

Language

English

Abstract

Bone tissue engineering using stem cells with osteogenic potential is a promising avenue of research for bone defect reconstruction. Organic, inorganic, and composite scaffolds have all been engineered to provide biomimetic microenvironments for stem cells. These scaffolds are designed to promote stem cell osteogenesis. Here, we review current technologies for developing biomimetic, osteoinductive scaffolds for stem cell applications. We summarize the reported in vitro and in vivo osteogenic effects of these scaffolds on stem cells.