Journal of the Korean Society of Pediatric Nephrology  2014;18(2):123-127

doi:10.3339/jkspn.2014.18.2.123

Three Cases of Erythema Multiforme Developed during Deflazacort Therapy in Children with Nephrotic Syndrome.

Seung Jin LEE 1 ; Bong Hwa KANG ; Min Hyun CHO

Affiliations

+expand

Keywords

Erythema multiforme; Stevens-Johnson syndrome; Nephrotic syndrome; Deflazacort

Country

Republic of Korea

Language

English

Abstract

Erythema multiforme (EM) is an acute mucocutaneous disorder involving the skin, mouth, eyes, and genital organs. It is classified into EM minor and EM major according to the involvement of the mucosal membrane. Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) belong to EM major. Compared to EM minor, SJS presents with more severe and progressive symptoms, and has a higher mortality rate. Corticosteroids are used in the treatment of EM. We report three cases of EM (two cases of EM minor and one case of SJS) that developed during treatment with oral corticosteroid (deflazacort; Calcort(R)) in children with nephrotic syndrome.