Journal of the Korean Society of Pediatric Nephrology  2014;18(2):128-131

doi:10.3339/jkspn.2014.18.2.128

A Case of "Full-house" Nephropathy in a Non-lupus Patient.

Ha Yeong YOO 1 ; Mikyung SON ; Myung Hyun CHO ; Byung Ok KWAK ; Hye Won PARK ; So Dug LIM ; Sochung CHUNG ; Kyo Sun KIM

Affiliations

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Keywords

Lupus nephritis; Immunofluorescence; Systemic lupus erythematosus; Biopsy

Country

Republic of Korea

Language

English

Abstract

Histopathologic evidence of "full-house" immune complex deposits is a pathognomonic feature of lupus nephritis. This report presents the case of a 12-year-old boy with persistent microscopic hematuria and proteinuria. He was diagnosed with "full-house" nephropathy based on a renal biopsy. However, there was no other clinical or biological evidence of systemic lupus erythematosus (SLE). Although the potential for isolated "full-house" nephropathy preceding SLE is unclear, such patients should be followed for clinical signs and autoantibodies of SLE. In most cases, microscopic hematuria has a good prognosis, and follow-up usually requires only regular urinalysis. However, we should be aware of isolated "full-house" nephropathy that remains asymptomatic for a long time, as few patients with no clinical signs and negative serology ultimately develop SLE.