Immune Network  2013;13(5):177-183

doi:10.4110/in.2013.13.5.177

Nanoparticle-Based Vaccine Delivery for Cancer Immunotherapy.

Yeong Min PARK 1 ; Seung Jun LEE ; Young Seob KIM ; Moon Hee LEE ; Gil Sun CHA ; In Duk JUNG ; Tae Heung KANG ; Hee Dong HAN

Affiliations

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Keywords

Nanoparticle; Cancer; Vaccine; Immunotherapy

Country

Republic of Korea

Language

English

Abstract

Development of nano-sized carriers including nanoparticles, nanoemulsions or liposomes holds great potential for advanced delivery systems for cancer immunotherapy, as such nanostructures can be used to more effectively manipulate or deliver immunologically active components to specific target sites. Successful development of nanotechnology based platform in the field of immunotherapy will allow the application of vaccines, adjuvants and immunomodulatory drugs that improve clinical outcomes for immunological diseases. Here, we review current nanoparticle-based platforms in the efficacious delivery of vaccines in cancer immunotherapy.