The Korean Journal of Gastroenterology  2015;65(6):366-369

doi:10.4166/kjg.2015.65.6.366

A Case of Disseminated Intra-abdominal Gastrointestinal Stromal Tumor Managed with Low Dose Imatinib.

Bo Hyun JANG 1 ; Byung Wook KIM ; Keun Joon LIM ; Boo Gyoung KIM ; Sung Min PARK ; Joon Sung KIM ; Jeong Seon JI ; Hwang CHOI

Affiliations

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Keywords

Gastrointestinal stromal tumors; Imatinib

Country

Republic of Korea

Language

English

Abstract

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. Imatinib mesylate is recommended as adjuvant therapy for GIST after surgical resection. However, drug-related adverse events are common. A 74-year-old female with metastatic GIST who was managed with imatinib experienced severe adverse events, including skin rashes, tremor, and alopecia, etc. The imatinib dose was reduced and the size of the metastatic GIST continued to decrease and adverse events showed significant improvement.