Journal of the Korean Society of Magnetic Resonance in Medicine  2014;18(1):59-63

doi:10.13104/jksmrm.2014.18.1.59

SAPHO Syndrome in a Patient with Breast Cancer Mimicking Bone Metastasis: A Case Report.

Kyungran KO 1 ; Hee Jung SUH ; Ji Young YOU ; So Youn JUNG ; Youngmee KWON ; Young Whan KOH

Affiliations

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Keywords

Breast cancer; SAPHO syndrome; Costosternoclavicular region

Country

Republic of Korea

Language

English

Abstract

A 66-year-old woman was transferred to our hospital due to her right breast cancer. Preoperative breast MRI shows 1.9 cm malignancy on her right breast (cT1N0M0) and incidentally found osteosclerotic change of left coststernoclavicular region. Bone scintigraphy showed hot uptake and the possibility of bone metastasis was not excluded. However, because the bone metastasis is not common in early stage cancer and the costosternoclavicular region is not common site, other possibility should be considered. SAPHO syndrome can be diagnosed even in the absence of dermatosis when there is an axial or appendicular osteitis and hyperostosis, especially in costosternoclavicular region. Though breast imaging specialists are not accustomed to this disease entity, awareness and diagnosis of the SAPHO syndrome can help differentiate bone metastasis.