Tuberculosis and Respiratory Diseases  2008;64(2):153-157

doi:10.4046/trd.2008.64.2.153

A Case of Different Response of Miliary Lung and Intracranial Nodules to Antituberculous Therapy.

Kwang Young PARK 1 ; Ho Jin LEE ; Jae Wook JUNG ; Yoon Hee CHOI ; Seung Bum NAM ; Se Han AHN ; Cheol Hyeon KIM ; Jae Cheol LEE

Affiliations

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Keywords

Tuberculosis; Paradoxical response; Intracranial tuberculoma

Country

Republic of Korea

Language

Korean

Abstract

Although a paradoxical response of tuberculosis to antituberculous therapy is not a rare phenomenon, it can be a clinical challenge to differentiate a paradoxical response from treatment failure. A 25-year-old woman was admitted for miliary lung nodules and multiple intracranial nodules. Antituberculous treatment was started with a preliminary diagnosis of tuberculosis based on the history and clinical findings. After one month, the miliary lung nodules improved while the intracranial nodules increased in size and number. Based on a stereotactic biopsy, it was confirmed that the intracranial lesions were tuberculomas. Although the therapeutic regimen was not changed, the symptoms eventually were ameliorated and the intracranial nodules improved two months later.