The World Journal of Men's Health  2017;35(3):178-185

doi:10.5534/wjmh.16032

The Correlation between Body Mass Index and Routine Parameters in Men Over Fifty.

Deok Ha SEO 1 ; Sol YOON ; Jae Hwi CHOI ; Jungmo DO ; Sin Woo LEE ; Chunwoo LEE ; Seong Uk JEH ; See Min CHOI ; Sung Chul KAM ; Jeong Seok HWA ; Ky Hyun CHUNG ; Sung Won KWON ; Sae Chul KIM ; Dong Soo PARK ; Jae Mann SONG ; Kyung Seop LEE ; Jae Seog HYUN

Affiliations

+expand

Keywords

Body mass index; Lower urinary tract symptoms; Prostate-specific antigen; Prostatic hyperplasia

Country

Republic of Korea

Language

English

Abstract

PURPOSE: This study aimed to investigate the relationships between body mass index (BMI) and prostate-specific antigen (PSA) levels, international prostate symptom score (IPSS), quality of life (QoL), and prostate volume (PV). MATERIALS AND METHODS: Height, weight, PSA levels, PV, and IPSS were analyzed in 15,435 patients who underwent a prostate examination between 2001 and 2014. Patients aged <50 years or with a PSA level ≥10 ng/mL were excluded. The relationships between BMI and PSA, IPSS, QoL, and PV were analyzed by a scatter plot, one-way analysis of variance, and the Pearson correlation coefficient. RESULTS: The mean age was 71.95±7.63 years, the mean BMI was 23.59±3.08 kg/m2, the mean PSA level was 1.45±1.45 ng/mL, the mean IPSS was 15.53±8.31, the mean QoL score was 3.48±1.25, and the mean PV was 29.72±14.02 mL. PSA, IPSS, and QoL showed a tendency to decrease with increasing BMI, and there were statistically significant differences for each parameter (p≤0.001). PV showed a significant tendency to increase with BMI (p < 0.001). In the correlation analysis, BMI showed a statistically significant correlation (p < 0.001) with PSA, IPSS, and QoL, although the correlations were very weak. In contrast, BMI showed a significant correlation with PV (p < 0.001), with a meaningful Pearson correlation coefficient of 0.124. CONCLUSIONS: Higher BMI was associated with lower PSA levels and higher IPSS and QoL scores. Meanwhile, PV increased with BMI. Although obese individuals had a greater PV, obesity did not aggravate lower urinary tract symptoms.