Journal of Gynecologic Oncology  2009;20(3):187-191

doi:10.3802/jgo.2009.20.3.187

A case of neutrophilia related to a cytokine-producing relapsed squamous cell carcinoma of the uterine cervix arising from the rectovaginal septum.

Geon PARK 1 ; Young Jin PARK ; Yo Sup LIM ; Tae Gyu AHN ; Sei Jun HAN

Affiliations

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Keywords

Squamous cell carcinoma; Uterine cervix; Paraneoplastic syndrome; G-CSF; IL-6

Country

Republic of Korea

Language

English

Abstract

Paraneoplastic neutrophilia caused by a squamous cell carcinoma of the uterine cervix has been seen rarely. We report a case of relapsed squamous cell carcinoma of the uterine cervix with severe neutrophilia, rapid tumor growth and aggressive clinical course, possibly due to autocrine stimulation of cell growth by G-CSF and IL-6 without other possible causes of neutrophilia.