Korean Journal of Anesthesiology  1993;26(2):293-298

doi:10.4097/kjae.1993.26.2.293

Cardiovascular Effect of Lidocaine in Patients under Halothane , Enflurane and Diazepam Anesthesia.

Bong Ho SHIN 1 ; Sang Hyun GWAK ; Sung Su CHUNG ; In Ho HA

Affiliations

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Keywords

Anesthetics; halothane; enflurane; diazepam; local Anesthetics; lidocaine; Cardiovascular effect

Country

Republic of Korea

Language

Korean

Abstract

To evaluate the cardiovascular effect of lidocaine and serum electrolytes during inhalational or intravenous anesthesia, thirty-two healthy patients were randomly divided into three groups and measured systolic pressure, diastolic pressure, mean pressure, heart rate and serum K+ and Na+ level were measured at 30 sec, l, 3, 6, 12 minutes after intravenous injection of lidocaine(1.5 mg/kg) during halothane-N2O-O2 or enflurane-N2O-O2 or diazepam-N2O-O2 anesthesia. In all 3 groups, the values of hemodynamic and serum electrolytes were not changed by 2% lidocaine. These results indicate that intravenous injection of lidocaine(1.5 mg/kg) to prevent undesirable reflexes and to prevent intracranial hypertension is a safe method without depression of hemodynamics.