The quantification of markers of breast cancer in healthy people (26 people for CA 15-3 and 28 people for CEA) by IRMA has shown that the serum concentration of CA15-3 and CEA was 19.12+/- 15.44 u/ml and 4.19 +/- 2.35 ng/ml, respectively. The medium (4.48), mininum (0.00) and maxinum (8.37) ng/ml. These results can be used to compared with markers in patients with breast cancer. There was no difference of these between men and women.