Cancer Research and Treatment  2007;39(2):88-91

A Case of Organizing Pneumonia Associated with Rituximab.

Chi Hoon MAENG 1 ; Sang Ouk CHIN ; Byung Hyuk YANG ; Si Young KIM ; Hwi Joong YOUN ; Kyung Sam CHO ; Sun Kyung BAEK ; Sun LEE

Affiliations

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Keywords

Rituximab; Organizing pneumonia; Non-Hodgkin's lymphoma

Country

Republic of Korea

Language

English

Abstract

Rituximab is a human/murine chimeric anti-CD20 mono- clonal antibody used to treat CD20-positive B-cell non- Hodgkin's lymphoma (NHL). Although most of the adverse effects associated with rituximab are usually reversible and temporary infusion-related reactions, including fever, chills, flushing and skin reactions, there are several reports of pulmonary events after long-term administration of rituximab. We present a case of asymp-tomatic nodular organizing pneumonia occurring during rituximab-based chemotherapy in a patient with non- Hodgkin's lymphoma.