Korean Journal of Endocrine Surgery  2015;15(4):86-92

doi:10.16956/kjes.2015.15.4.86

Prediction of Nodal Metastasis by the AMES Scoring System in Patients with Papillary Thyroid Cancer.

Youn Ju LEE 1 ; Je Ryong KIM

Affiliations

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Keywords

Papillary thyroid carcinoma; Central lymph node; AMES; Lymph node metastasis; Positron emission tomography-computed tomography

Country

Republic of Korea

Language

English

Abstract

PURPOSE: We assessed the prognostic value of AMES to determine the extent of surgery in PTC patients, and compared AMES score usefulness and accuracy with [18F] FDG PET/CT. METHODS: We conducted a review of data from a single center and a single surgeon, who treated 341 patients with PTC with total thyroidectomy and prophylactic bilateral CLN dissection at a tertiary referral center, Chungnam National University Hospital, between 2001 and 2012. RESULTS: In multivariate analysis, the rate of CLN metastasis was considerably higher in PTC patients with the higher AMES score (odds ratio [OR], 1.718; 95% confidence interval [CI], 1.073~2.752), higher SUV of the CLN (>0) (OR, 6.525; CI, 3.184~13.371), higher SUV of the tumor (>4.3) (OR, 1.855; CI, 1.065~3.231). CONCLUSION: The AMES score is helpful in deciding whether to perform a CLN dissection, as there is a strong association between the AMES score and CLN metastasis. This high predictive value of CLN metastasis can help determine the extent of PTC surgery while considering the cost and effort.