Korean Journal of Pediatric Hematology-Oncology  2003;10(2):277-281

Evans Syndrome Following Unrelated Bone Marrow Transplantation.

Young Myoung KIM 1 ; Bong Jin KIM ; Young Ho LEE

Affiliations

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Keywords

Immune cytopenia; Evans syndrome; Hematopoietic stem cell transplantation

Country

Republic of Korea

Language

Korean

Abstract

Thrombocytopenia and Coombs' positive hemolytic anemia (Evans syndrome) after hematopoietic stem cell transplantation (HSCT) rarely occurs, especially in childhood. We experienced a case of Evans syndrome following unmanipulated unrelated bone marrow transplantation, which promptly responded to steroid pulse therapy. Immune-mediated cytopenia should be considered for evaluation of post-engraftment cytopenia following HSCT.