Journal of Liver Cancer  2016;16(1):42-46

doi:10.17998/jlc.2016.16.1.42

A Case of Rapid Progressive Extrahepatic Metastasis of Hepatocellular Carcinoma after Surgical Resection for Huge Single Mass.

Eun Sun JANG 1 ; Haeryoung KIM ; Young Rok CHOI ; Jai Young CHO ; Yoo Seok YOON ; Ho Seong HAN ; Ji Hyun KIM ; Jin Wook KIM ; Sook Hyang JEONG

Affiliations

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Keywords

Hepatocellular carcinoma; Classification; Metastasis; Prognosis

Country

Republic of Korea

Language

Korean

Abstract

Hepatocellular carcinoma (HCC) shows a poor prognosis with high recurrence rate even after surgical resection. To improve prognosis of HCC patient, regular surveillance for high-risk group is recommended, but cost-benefit of the surveillance under 40 years old Asian male with hepatitis B infection is unclear. We share a 39-year-old male case which showed early recurrence and rapid extrahepatic metastasis after surgical resection for single huge HCC. Based on the pathologic finding, this case was diagnosed with 'stemness'-related marker-expressing HCC. Further molecular classification for HCC could be beneficial to estimate individual risk for HCC recurrence and to predict prognosis.