Korean Journal of Pediatrics  2005;48(3):321-326

A Case of Multiple Giant Coronary Aneurysms with Large Mural Thrombus due to Kawasaki Disease in a Young Infant.

Eun Na CHOI 1 ; Jeoung Tae KIM ; Yuria KIM ; Byung Won YOO ; Deok Young CHOI ; Jae Young CHOI ; Jun Hee SUL ; Sung Kye LEE ; Dong Soo KIM ; Young Hwan PARK

Affiliations

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Keywords

Mucocutaneous lymph node syndrome; Coronary aneurysm; Coronary thrombosis; Infant; Myocardial ischemia

Country

Republic of Korea

Language

Korean

Abstract

Kawasaki disease is an acute systemic vasculitis of unknown origin. Giant coronary aneurysm is one of the most serious complications, although peripheral artery vasculitis can produce life-threatening events. Myocardial ischemia and infarction can be caused by coronary artery stenosis, aneurysm, and stagnation of blood flow in coronary arteries which triggers thromboembolism. Atypical presentation in young infants often interferes with prompt diagnosis and timely treatment, resulting in poor outcomes. We describe a 3-month-old infant with multiple giant coronary aneurysms with flow stagnation, stenosis and large mural thrombus due to Kawasaki disease. He presented with a prolonged course of severe coronary involvement in spite of all measures to reduce coronary complications. Finally, surgical intervention was tried because of the worsening coronary artery abnormalities. The patient died of acute cardiorespiratory failure shortly after weaning from cardiopulmonary bypass.