Korean Journal of Pediatrics  2005;48(3):342-345

A Case of Neonatal Lupus Erythematosus Associated with Anti-U1RNP Antibodies.

Byung Hoon AHN 1 ; Gu Chang LEE ; Tae Young YOON ; Mi Jung KIM

Affiliations

+expand

Keywords

Neonatal lupus erythematosus; U1RNP antibody

Country

Republic of Korea

Language

Korean

Abstract

Neonatal lupus erythematosus(NLE) is a distinct subset of lupus characterized by cutaneous findings, cardiac conduction defects, hepatic or hematologic abnormalities. These manifestations are associated with the presence of maternal auto-antibodies such as anti-SSA/Ro, anti-SSB/La, and rarely anti- RNP(U1RNP) antibodies. Cases of U1RNP antibody-positive NLE have somewhat atypical cutaneous manifestation without cardiac or systemic abnormalities. We report a case of cutaneous NLE associated with U1RNP antibodies.