Journal of Clinical Neurology  2007;3(2):116-119

doi:10.3988/jcn.2007.3.2.116

Polyneuropathy Associated with IgA Paraproteinemia and Amyloidosis: A Case Report and Literature Review.

Yunsook JHANG 1 ; Jung Ju LEE ; Jong Moo PARK ; Ja Seong KOO ; Byung Kun KIM ; Ohyun KWON

Affiliations

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Keywords

Amyloidosis; Paraproteinemia; Polyneuropathy

Country

Republic of Korea

Language

English

Abstract

Paraproteinemia potentially causes peripheral neuropathy via an unknown underlying pathogenetic mechanism. We report a case of pathologically proven amyloid neuropathy with AL amyloidosis with an IgA kappa light chain, which was initially diagnosed as neuropathy associated with monoclonal gammopathy of undetermined significance. This case indicates that in cases of neuropathy with paraproteinemia, the other potential causes should be excluded by appropriate means, especially pathological evaluations.