Journal of Clinical Neurology  2007;3(1):53-56

doi:10.3988/jcn.2007.3.1.53

Mild Encephalopathy with Reversible Lesion in the Splenium of the Corpus Callosum and Bilateral Frontal White Matter.

Jeong Seon CHO 1 ; Sang Won HA ; Young Su HAN ; Sang Eun PARK ; Ki Moo HONG ; Jeong Ho HAN ; Eun Kyoung CHO ; Doo Eung KIM ; Jea Geun KIM

Affiliations

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Keywords

Reversible Lesion; Splenium; Corpus Callosum; Encephalitis/Encephalopathy

Country

Republic of Korea

Language

English

Abstract

A 59-year-old man visited an emergency room due to the sudden onset of severe dysarthria with a drowsy mental status. MRI demonstrated T2 prolongation and restricted diffusion involving the splenium of the corpus callosum and bilateral frontal white matter neurological signs and symptoms were mild, and the recovery was complete within a week. Follow-up MRI performed one month later revealed complete resolution of the lesions. The clinical and radiological courses were consistent with previously reported reversible isolated splenial lesions in mild encephalitis/encephalopathy except for the presence of frontal lesions. This case suggests that such reversible lesions can occur outside the splenium.