Korean Journal of Gastrointestinal Endoscopy  2007;34(6):334-338

A Case of Gastrointestinal Stromal Tumor of the Jejunum with Obscure Gastrointestinal Hemorrhage Diagnosed by Exploratory Laparotomy.

Hae Bin JUNG 1 ; Sun Young KIM ; Shin Ae PARK ; Sang Mi PARK ; Kon Ho SHIM ; Eui Hyung KIM ; Eun Jung JEON ; Jung Hwan OH ; Jeong Jo JEONG ; Sang Wook CHOI

Affiliations

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Keywords

Gastrointestinal stromal tumor; Gastrointestinal hemorrhage; Laparotomy

Country

Republic of Korea

Language

Korean

Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the gastrointestinal tract, and they represent about 2% of all neoplasms of the gastrointestinal tract. GISTs primarily affect the stomach (50~60%), but they can also affect the small intestine (20~30%), large intestine (7%) and esophagus (1%). The clinical manifestations of GISTs vary according to the location and size of the mass. GISTs are generally KIT (CD117)-positive and are diagnosed by immunohistochemistry. Tumor size and mitotic activity are the best predictive prognostic features. The treatment of choice for primary GIST is complete surgical resection with a negative margin. A 78-year-old man who presented with melena and diffuse abdominal pain was admitted to our hospital. Esophagogastroduodenoscopy, colonoscopy, angiography and an RBC scan were performed but we were unable to locate the focus of the hemorrhage. A gastrointestinal stromal tumor (GIST) of the jejunum was diagnosed after laparotomy.