Journal of the Korean Neurological Association  2011;29(2):133-135

Pseudohypoparathyroidism Presented With Seizure.

Minho HWANG 1 ; Yu Ri JEONG ; Kyusik KANG ; Jong Moo PARK ; Ohyun KWON ; Byung Kun KIM ; JungJu LEE

Affiliations

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Keywords

Pseudohypoparathyroidism; Seizures; Electroencephalogram

Country

Republic of Korea

Language

Korean

Abstract

Pseudohypoparathyroidism (PHP) is a rare clinical syndrome characterized by hypocalcemia, hyperphosphatemia and increase of serum parathyroid hormone in association with unique clinical features. We recently experienced a typical PHP type Ia patient who presented with recurrent seizure and muscle spasms and electroencephalogram (EEG) showed generalized spike-and-wave discharges. With the correction of hypocalcemia, seizures did not recur and epileptiform discharges disappeared. We suggest that the possibility of PHP should be considered in patients with seizures showing hypocalcemia and hyperphosphatemia.