Korean Journal of Dermatology  1977;15(1):63-67

Therapeutic Efficacy of Topical 5-Fluorouracil for Zosteriform Porokeratosis.

Shi Ryong KIM ; Joo Bong LEE ; Won HOUH

Country

Republic of Korea

Language

Korean

Abstract

The patient, 23 year old female, with the Zosteriform Porokeratosis on right side of trunk and extrimity and a superimposed Disseminated Superficial Actinic Porokeratosis on face, was treated at Dept. of Dermatology, Catholic Medical College. The lesions appeared at the age of 7. Her mother had similar lesions on the face and extrimities. 3% 5-Fluorouracil in Vanishing cream base was applied topically under occlusive dressing for 40 days, and the dressing was changed every 24 hours. On seventh day erythema and papular lesion appeared, and oral administration of steroid and intermittent topical betamethasone dressing was enable to continued the occlusive dressing. One year after the treatment the lesion did not recurred and shallow atropic scar were left with normal skin color.