The Korean Journal of Pain  2013;26(1):80-83

doi:10.3344/kjp.2013.26.1.80

Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus: A Case Report.

Hyun Min BAE 1 ; Yoo Jung PARK ; Young Hoon KIM ; Dong Eon MOON

Affiliations

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Keywords

carbamazepine; drug hypersensitivity reaction; Stevens-Johnson syndrome; trigerminal neuralgia

Country

Republic of Korea

Language

English

Abstract

Stevens-Johnson syndrome (SJS) is a rare but life-threatening skin reaction disease and carbamazepine is one of its most common causes. We report a case of SJS secondary to carbamazepine in a patient with previous pruritus due to carbamazepine which was given for treatment of trigeminal neuralgia. We would like to caution all providers that carbamazepine readministration should be avoided in the patient with a previous history of SJS or adverse skin reaction. In addition, we strongly recommend gradual titration when initiating treatment with carbamazepine.