Pediatric Allergy and Respiratory Disease  2009;19(3):209-219

Treatment of Atopic Dermatitis: an Update and Review of the Literature.

Tae Yoon KIM 1

Affiliations

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Keywords

Atopic dermatitis; Biologics; Calcineurin inhibitors; Immunomodulatory drugs

Country

Republic of Korea

Language

Korean

Abstract

Atopic dermatitis is a chronic, relapsing, inflammatory skin disease, with genetic and environmental backgrounds. Successful management of atopic dermatitis requires a multipronged approach. Management should compromise of a disease-adapted treatment which combines adjuvant basic therapy, symptomatic relief and, if needed, anti-inflammatory treatment and the identification and avoidance of trigger factors. Topical calcineurin inhibitors are also considered to be good alternatives for the long-term control of severe atopic dermatitis. Also, new therapies such as immunomodulatory drugs, biologics, anti-IgE therapy, and CpG oligodeoxynucleotides (ODN) are considered to be effective in treatment of atopic dermatitis.