Journal of the Korean Society of Echocardiography  2000;8(1):54-58

Effect of a Meal on Cardiac Performance in Patients with Coronary Artcry Disease.

Hun Sik PARK 1 ; Bong Ryul LEE ; Eui Ryong JUNG ; Dong Hoon GWAK ; Dong Hun YANG ; Seung Chul SHIN ; Jong Hyun HWANG ; Yong Geun JO ; Sung Chul CHAE ; Jae Eun JEON ; Eui Hyun PARK

Affiliations

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Keywords

Coronary artery disease; Mixed meal; Cardiac performance

Country

Republic of Korea

Language

Korean

Abstract

BACKGROUND: It has been well recognized that exercise tolerance and angina threshold in patients with coronary artery disease (CAD) are reduced after a meal. But precise mechanism leading to the postprandial worsening of angina has yet to be adequately defined. This study was undertaken to determine the effect of a mixed meal on cardiac performance and heart rate variability (HRV) in patients with CAD. METHODS: 24 patients with angina or myocardial infarction were studied. Echocardiographic examination and heart rate variability test were performed in the fasting state and the other 40-60 minutes after a 600-800 kcal mixed meal. RESULTS: In the postprandial state, resting heart rate was significantly increased by 5.2% from 64.8+/-10.69 beats/min to 68.2+/-10.2 beats/min (p<0.01), stroke volume by 8.1% from 59.6+/-17.3 ml to 64.4+/-18.1 ml (p<0.01), cardiac output by 14.2% from 3.8+/-1.06 to 4.3+/-1.21 (p<0.01). E wave and A wave of mitral filling flow and E/A ratio were not significantly different in the fasting and postprandial tests. But DT and IVRT were significantly increased in the postprandial state (p<0.05, p<0.01 respectively). HRV was not different in the fasting and postprandial state. CONCLUSIONS: In patients with CAD, a 600-800 kcal mixed meal significantly increased resting heart rate, stroke volume, cardiac output, DT and IVRT.