Korean Journal of Pediatric Hematology-Oncology  2001;8(2):378-381

A Case of Malignant Melanoma in Children.

Joong Hyun BIN 1 ; Pil Sang JANG ; Soh Yeon KIM ; Nak Gyun CHUNG ; Bin CHO ; Soon Ju LEE ; In Goo LEE ; Hack Ki KIM

Affiliations

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Keywords

Malignant melanoma; Giant congenital melanocytic nevus; Childhood

Country

Republic of Korea

Language

Korean

Abstract

Malignant melanoma is a very rare disease in children. There is an increased risk for the development of malignant melanoma in patient with giant congenital melanocytic nevus. The manifestations of distant metastases in malignant melanoma commonly indicate a poor prognosis. First line treatment of malignant melanoma is excision, but when associated with giant congenital melanocytic nevus, excision is very difficult due to the site and the size of the lesions. However, malignant melanoma is not sensitive to chemotherapy, but a child is more sensitive than an adult. We report a case of unresectable childhood malignant melanoma associated with a giant congenital melanocytic nevus in a 3 year-old female treated with chemotherapy.