Intestinal Research  2010;8(2):177-180

doi:10.5217/ir.2010.8.2.177

A Pityrosporum Fungal Infection Following Infliximab Therapy in a Crohn's Disease Patient.

Keun Young SHIN 1 ; Jun HEO ; Min Kyu JUNG ; Seong Woo JEON ; Sung Kook KIM

Affiliations

+expand

Keywords

Crohn Disease; Infliximab; Pityriasis Versicolor

Country

Republic of Korea

Language

English

Abstract

Crohn's disease (CD) is a chronic immune-mediated inflammatory disorder. Treatment strategies for CD are targeted toward various components of the proinflammatory mediators and subsequent immune response. Recently, the anti-tumor necrosis factor (TNF) monoclonal antibody, infliximab has been used in patients with CD. However, uncommon and unusual infections have been reported during anti-TNF-alpha therapy and immunomodulator. Here, we report a case of pityriasis versicolor occurring in a patient with CD receiving infliximab treatment. The patient was successfully treated with topical ketoconazole.