Journal of Rheumatic Diseases  2015;22(2):127-131

doi:10.4078/jrd.2015.22.2.127

A Case of Palmoplantar Pustulosis Present in the Daughter of a SAPHO Syndrome Patient.

Ji Young CHOI 1 ; Jae Min KIM ; Ran SONG ; Yeon Ah LEE ; Sang Hoon LEE ; Hyung In YANG ; Seung Jae HONG

Affiliations

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Keywords

SAPHO syndrome; Acquired hyperostosis syndrome; Palmoplantaris pustulosis

Country

Republic of Korea

Language

Korean

Abstract

SAPHO syndrome is a rare inflammatory, pseudoinfectious disease. Initially it was an acronym for Syndrome Acne Pustulosis Hyperostosis Osteitis, and the meaning of S was later changed to synovitis. It occurs predominantly in children and adults and is not common over 60 years. The most common clinical presentation is osteoarticular involvement at the anterior chest wall and skin manifestations may be evident, but it could occur years earlier or develop later. We report on two cases of mother and daughter. A 51-year-old female was diagnosed with SAPHO syndrome with costochondritis and palmoplantar pustulosis. Five years later, her 31-year-old daughter presented with similar skin manifestations of the hand and foot.