Korean Journal of Dermatology  2011;49(1):86-89

Neutrophilic Dermatosis of the Dorsal Hands.

Se Rim CHOI 1 ; Woo Joong KIM ; Hee Jung LEE ; Dong Hyun KIM ; Moon Soo YOON

Affiliations

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Keywords

Dorsal hand; Neutrophilic dermatosis; Sweet syndrome

Country

Republic of Korea

Language

Korean

Abstract

Neutrophilic dermatosis of the dorsal hands (NDDH) is a rare, localized variant of Sweet syndrome, and it was first described by Galaria et al. in 2000. It usually occurs in middle-aged women and it is characterized by erythematous papules, plaques, pustules and hemorrhagic bullae that are generally located on the dorsal hands. The histopathological findings show prominent papillary dermal edema and a dense dermal neutrophilic infiltration. A neutrophilic infiltrate can also cause a variable degree of vascular damage: endothelial cell swelling, RBC extravasation, leukocytoclasia and fibrin deposition within the walls of vessels. We report here on a case of NDDH in a 50-year-old man who was treated with oral corticosteroid and the NDDH recurred after 9 months.