Tuberculosis and Respiratory Diseases  2000;49(4):508-513

doi:10.4046/trd.2000.49.4.508

A Case of aspergillus tracheobronchitis in non-immunocompromise patient.

Hyo Young CHUNG ; Hwi Jong KIM ; Soo Hee KIM ; Jong Deog LEE ; Young Sil HWANG

Keywords

Tracheobronchitis; Invasive aspergillosis

Country

Republic of Korea

Language

Korean

Abstract

The aspergillus tracheobronchitis is distinctive manifestation of invasive aspergillosis, in which infection is limited completely or predominantly to the tracheobronchial tree. It accounts for about 7 to 10 percent of cases of invasive disease. Grossly, such disease may take the mucosal exudate and obstruct partially the airway lumen or completely the occlusive mucous/fungus plugs. Microscopically, the superficial portion of the airway wall is acutely inflamed and contain fungal hyphae. However, infection is often limited to the mucosa. We report a case of aspergillus tracheobrochits in a 54 year-old man who presented cough, progressive dyspnea with wheezing, and mucus plug. Bronchoscopy showed mucosal exudate and plug.Bronchoscopic biopsy showed aspergillus hyphae and inflammation in the mucosa. He was successfully treated with itraconazole.