Clinical Psychopharmacology and Neuroscience  2014;12(3):196-202

doi:10.9758/cpn.2014.12.3.196

Serotonin and Mental Disorders: A Concise Review on Molecular Neuroimaging Evidence.

Shih Hsien LIN 1 ; Lan Ting LEE ; Yen Kuang YANG

Affiliations

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Keywords

Serotonin; Mental disorders; Positron-emission tomography; Single photon emission computed tomography

Country

Republic of Korea

Language

English

Abstract

Serotonin is one of the most important neurotransmitters influencing mental health and, thus, is a potential target for pharmaco-logical treatments. Functional neuroimaging techniques, such as positron-emission tomography (PET) and single photon emission computed tomography (SPECT), could provide persuasive evidence for the association between mental disorders and serotonin. In this concise review, we focus on evidence of the links between serotonin and major depressive disorders, as well as other mood disorders, anxiety disorders, schizophrenia, addiction, attention deficit hyperactivity disorder (ADHD), and autism.