Korean Journal of Hepato-Biliary-Pancreatic Surgery  2013;17(4):186-190

doi:10.14701/kjhbps.2013.17.4.186

Collision tumor of the ampulla of Vater - Coexistence of neuroendocrine carcinoma and adenocarcinoma: report of a case.

Hee Joon KIM 1 ; Byung Gwan CHOI ; Choong Young KIM ; Chol Kyoon CHO ; Jin Woong KIM ; Jae Hyuk LEE ; Young Hoe HUR

Affiliations

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Keywords

Collision tumor; Ampulla of Vater; Neuroendocrine carcinoma; Adenocarcinoma

Country

Republic of Korea

Language

English

Abstract

Herein, we present a case of coexisting neuroendocrine carcinoma and conventional adenocarcinoma (collision tumor) in the ampulla of Vater, which has seldom been reported in the literature. A 51-year-old man presented with a month history of jaundice. MRCP disclosed about 1.9x1.8 cm sized heterogeneously enhancing mass in ampulla of Vater, causing obstructions of distal common bile duct. He underwent pylorus-preserving pancreaticoduodenectomy under the diagnosis on ampulla of Vater cancer. Pathologically, sections on the ampulla of Vater showed conventional ductal adenocarcinoma extended and collided with poorly differentiated neuroendocrine carcinoma. In conclusion, we hereby presented a case of coexisting neuroendocrine carcinoma and conventional adenocarcinoma in the ampulla of Vater.