Journal of Korean Epilepsy Society  2006;10(2):71-77

Biostatistical Methods for Epilepsy Trials.

Sung Min MYOUNG 1 ; Shin Young KIM

Affiliations

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Keywords

Epilepsy; Clinical trials; Biostatistics

Country

Republic of Korea

Language

Korean

Abstract

Clinical trial provide reliable basis for evaluating the efficacy and safty of new treatments. To proceed effectively with clinical trial requires an comprehension of the basic principles of clinical design and biostatistical methods. This review focuses on fundamentals of biostatistical theory, on studies of calculating sample size, on definitions for classsification of evidence in epilepsy trials and on examining biostatistical methods for evaluating efficacy of antiepileptic drugs. This review guide how to understand basic statistical concepts and types of study design for epilepsy trials.