The Journal of the Korean Rheumatism Association  2000;7(3):308-312

A Case of Periosteal New Bone Formation Associated with Behcet? Disease.

Dong Joo KEUM 1 ; Doo Kyoung YANG ; Kwang Jin KIM ; Sam Ryong JEE ; Chin Hyuk YUN ; Sung Won LEE ; Won Tae CHUNG

Affiliations

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Keywords

Behcet? disease; Hypertrophic osteoarthropathy

Country

Republic of Korea

Language

Korean

MeSH

Abstract

Behcet? disease is a recurring illness characterized by the triple symptom complex of aphthous stomatitis, genital ulceration, and uveitis. The disease is multisystemic disorder with involvement of skin, gastrointestinal tract, blood vessels, central nervous system, joints, and epididymis. Vascular involvement of Behcet? disease affects both arteries and veins and blood vessels of all sizes. Periosteal new bone formation is one feature of hypertrophic osteoarthropathy. Other features are clubbing and arthritis. Periosteal new bone formation on the bones of the lower extremities without other features of hypertrophic osteoarthropathy has been reported in patients with varicose veins, vitamin A intoxication, infantile cortical hyperostosis, tuberous sclerosis, congenital syphilis and chronic renal failure with hyperparathyroidism, and chronic venous insufficiency. However, periosteal new bone formation has not, to our knowledge, been described in patients with Behcet? disease yet although similar findings are occasionally noted in polyarteritis nodosa. We report a case of Behcet? disease complicated by leg swelling with periosteal new bone formation of right lower leg.