Pediatric Gastroenterology, Hepatology & Nutrition  2013;16(2):123-126

doi:10.5223/pghn.2013.16.2.123

Co-Infection with Cytomegalovirus and Helicobacter pylori in a Child with Menetrier's Disease.

Yangho YOO 1 ; Yoon LEE ; Yoo Min LEE ; Yon Ho CHOE

Affiliations

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Keywords

Menetrier's disease; Cytomegalovirus; Helicobacter pylori

Country

Republic of Korea

Language

English

Abstract

Menetrier's disease is a rare protein-losing gastropathy characterized by hypertrophic gastric fold, foveolar hyperplasia, and hypoproteinemia with resulting peripheral edema. It is clinically evident as nonspecific gastrointestinal symptoms, including abdominal discomfort, nausea and vomiting, abdominal pain, weight loss, diarrhea, and edema. Pediatric Menetrier's disease usually has an insidious onset and progressive, chronic clinical course and it spontaneously resolves in weeks or months. The pathogenesis of Menetrier's disease is not clearly understood. Menetrier's disease is thought to be associated with some gastric infections. But the cause of Menetrier's disease is unknown, an association with cytomegalovirus (CMV) and Helicobacter pylori has been suggested. In Korea, We present the first a case of pediatric Menetrier's disease with positive evidence of CMV and H. pylori.