An 82-year-old male patient with atrial fibrillation took atorvastatin calcium (20 mg/ d) by himself following advise of other person. About one month later,he developed muscular soreness, weakness,and brown urine. The results of laboratory tests showed myoglobin (Mb)> 3000 μg/ L,creatine kinase (CK) > 16000 U/ L,urea nitrogen 16. 0 mmol/ L,serum creatinine (Scr)347 μmol/ L,creatinine clearance 15 ml/ min. The patient was diagnosed as rhabdomyolysis and acute kidney injury which related to atorvastatin calcium. After the withdrawal of atorvastatin calcium and 13 days of treatments with fluid infusion,alkalizing urine,and diuretic,the patient′s muscular soreness and weakness were improved. The results of laboratory test showed Mb 2340 μg/ L,CK 61 U/ L,urea nitrogen 7. 1 mmol/ L,were Scr 189μmol/ L,and creatinine clearance 30 ml/ min. Urine test showed no abnormal results.