Objective To explore the reasons for the replacement of central venous catheter dressing and improve nursing in ICU patients.Methods Retrospective analysis was made on the reasons for the replacement of central venous catheter dressing in patients of the conventional group .By using integrated nursing method ,"menu-care"procedures were designed and implemented for the replacement of central venous catheter dressing, and patients applying the same nursing methods in the same period next year were used as the control.Results The reasons for the replacement of central venous catheter dressing in ICU patients were: looseness of the adhesive membrane, oozing of blood and oozing of fluid.Days of dressing maintenance for the conventional group were(2.35 ± 0.89)d, which were obviously fewer that those of the "menu-care"group (3.43 ±0.52) d, with statistical significance(P<0.05).CRBSI of the conventional group was 13.0%, which was higher than that of the"menu-care"group, also with statistical sig-nificance(P<0.05).Conclusion Proper nursing methods could increase the days of dressing maintenance and decrease the infection rate of CRBSI .