Cancer Research on Prevention and Treatment 2025;52(12):973-979

doi:10.3971/j.issn.1000-8578.2025.25.0550

Advancements in Cell Membrane–Based Biomimetic Carriers for Antitumor Therapy

Jiahe WU 1 ; Nan WANG 2 ; Jianqing GAO 3 ; Nengming LIN 1

Affiliations

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Keywords

Cell membrane-based biomimetic carrier; Drug delivery; Antitumor therapy

Country

China

Language

Chinese

Abstract

Drug delivery technologies are crucial components in drug development, greatly enhancing drug bioavailability and therapeutic efficacy and reducing toxic side effects. Cell membrane-based biomimetic carriers have attracted considerable interest owing to their intrinsic biointeractive capability derived from source cells in vivo. This review summarizes the fundamental properties and functional attributes of cell membrane–based biomimetic carriers from different cellular sources and discusses their advancements in tumor-targeted drug delivery and role in the activation of antitumor immunity. Ultimately, the discussion focuses on the prospects and potential challenges in employing cell membrane-based biomimetic carriers for antitumor treatment.