Philippine Journal of Neurology 2025;28(1):58-67
Functional outcomes after endovascular thrombectomy among patients with acute large vessel infarct: A Philippine single center experience
Kimberly Geronimo 1 ; Miguel Alejandro Baroque 1 ; Joann Soliven 1 ; Victor Erwin Joscon 1
Affiliations
Keywords
Endovascular Thrombectomy; Large Vessel Occlusions; Mechanical Thrombectomy; Thrombolysis
Country
Philippines
Language
English
MeSH
ACTIONS
ACTIONS
Abstract
BACKGROUND
Endovascular thrombectomy (EVT) is the gold standard of care for large vessel occlusion strokes, but is underutilized in developing countries.
METHODOLOGYThis single-center retrospective study included patients who underwent EVT during the period of September 2018 to April 2023. Data collected were demographics, underlying co-morbidities, use of anti-thrombotics/coagulants, CT or MR ASPECTS, thrombolysis prior to EVT, technique, timing, TICI score, occlusion site, discharge and 90-day MRS.
RESULTSOf the 1,595 stroke patients, 57 (3%) cases underwent EVT. The mean age was 65 with a male to female ratio of 6:5. Hypertension, atrial fibrillation, and diabetes were the common comorbidities. Majority of patients (90%, n=54) presented with moderate to severe disability (MRS 3-5). Majority were in the anterior circulation (89%, n=51). Stentriever technique was mostly used (59% n=34) with a 77% (n=44) recanalization rate. Early neurologic improvement (ENI) was seen in 7% (n=4), 2 of which translated to a favorable outcome after 90-days. Mortality occurred in 24% (n=14) of cases, mostly from neurological complications. 24% (n=14) had favorable outcome of MRS 0-2 after 90 days. Among those grouped in the unfavorable outcome, 53% (n=23) were MRS 3, still showing marked improvement of quality of life.
CONCLUSIONEVT outcomes in this study is aligned with the landmark trials which exhibited a number needed to treat of 2.8-7.4. This local data highlights that EVT is a possible and effective treatment for large vessel strokes despite wide gap in accessibility and use in the country.
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