Philippine Journal of Surgical Specialties 2025;80(1):20-23

doi:https://doi.org/10.61662/PCS_gzoy6812

Familial adenomatosis polyposis associated papillary thyroid carcinoma- cribriform morular variant: A case report

Jennifer A. Winter 1 ; Michelle C. Payagen 1 ; Mathew B. Bawayan 1

Affiliations

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Keywords

Cribriform Morular Variant

Country

Philippines

Language

English

Abstract

Familial Adenomatous Polyposis (FAP) is a multi-tumoral syndrome that includes neoplasms in the duodenum, brain, pancreas and thyroid. The Cribriform Morular Variant (CMV) is a rare form of Papillary Thyroid Cancer seen in patients with FAP. Presented here is a 32 year old female who initially presented with an anterior neck mass followed years later by a rectal mass. She was diagnosed with FAP and colorectal adenocarcinoma and underwent total proctocolectomy with end ileostomy. She subsequently underwent a total thyroidectomy which revealed CMV Papillary Thyroid Carcinoma (CMV-PTC). Since FAP can have diverse presentations, a high index of suspicion is needed in order to make an earlier diagnosis to reduce potential morbidity and mortality. Papillary thyroid carcinoma can predate colonic polyposis. Identifying CMV-PTC early on can serve as an opportunity diagnose FAP early.