Philippine Journal of Pathology 2025;10(1):1-5

doi:https://doi.org/10.21141/PJP.2025.01

Infiltrative basal cell carcinoma with nodal metastasis in a 74-year-old female: A case report

Reynaldo Gabriel Paulino 1 ; John Ricardo Chua 2 ; Karen Damian 3 ; Erwin Gerard Geron 2 ; Clarisse Veronica Mirhan 1

Affiliations

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Keywords

Squamous Cell Carcinoma In-situ; Infiltrative Basal Cell Carcinoma; Basaloid Cells

Country

Philippines

Language

English

Abstract

Basal cell carcinoma, the most common human malignancy, has a rare incidence of metastases ranging from 0.0028-0.55%. We report a case of a 74-year-old female with a 10-year history of an enlarging anterior thigh nodule. Wide resection and inguinal lymph node dissection revealed an infiltrative basal cell carcinoma with lymph node metastasis due to the presence of basaloid cells, limited peripheral palisading, loose stroma, extensive spread, perineural invasion and immunoreactivity to p40, BerEP4, and GATA3.