Drug Standards of China 2024;25(2):109-117

doi:10.19778/j.chp.2024.02.001

Application of process analytical technology in advanced manufacturing of dermal drug delivery products

Yidian WANG 1 ; Huafei LUO

Affiliations

+expand

Keywords

continuous manufacturing; process analytical technology; critical quality attributes; dermal drug deliv-ery products; chemometrics

Country

China

Language

Chinese

Abstract

Process analysis technology(PAT)is of great significance to improve the process control and quality as-surance in the manufacture of dermal drug delivery products.This paper reviewed the application of PAT technology in the advanced manufacturing of dermal drug delivery products,introduced the basic situation of PAT and chemo-metrics,and summarized the commonly used PAT tools and their application examples in recent years.In the fu-ture,PAT will play a greater role in the process ofdermal drug delivery products,but the research in this area is still very scarce now.