Objective? To explore the effects of standardized nutritional nursing process in severe acute pancreatitis (SAP) patients. Methods? From January 2015 to June 2016, we selected 85 SAP patients at Zhejiang Province People's Hospital & People's Hospital of Hangzhou Medical College in control group by convenience sampling. From July 2016 to December 2017, we selected 88 SAP patients in observation group. Two groups all carried out enteral nutrition. Control group received routine nutritional nursing, while observation group implemented standardized nutritional nursing process. We compared the feeding intolerance, feeling related complications, standard-reaching rate of nutrition and nutritional status of patients between two groups. Results? There were 2 cases with vomit, 10 cases with abdominal distension, 5 cases with constipation, all with diarrhea (2.4±0.6) times a day, 5 cases with elevated intra-abdominal pressure and 1 case with abdominal compartment syndrome in observation group less than those in control group with statistical differences (P＜0.05). The incidence of feeling related complications of observation group was lower than that of control group with a statistical difference (P＜0.01). At the seventh day, the standard-reaching rate of nutrition of observation group and control group was 89.8% and 71.8% respectively with a statistical difference (χ2=8.083, P＜0.01). At the fourteenth day, the nutrition indicators such as prealbumin, serum albumin, triceps skin-fold thickness and arm muscle circumference of patients in observation group were higher than those in control group (P＜ 0.05). The residence time in intensive care unit, proportion of mechanical ventilation and time of mechanical ventilation of observation group were statistically lower than those of control group (P＜ 0.05). Conclusions? The implementation of standardized nutritional nursing process in SAP patients can reduce the feeling related complications and feeding intolerance to improve nutritional status which is worth to be used widely in clinical application.