Laboratory Animal Research  2010;26(2):215-218

doi:10.5625/lar.2010.26.2.215

A Tumoral Calcinosis Case in a Beagle Dog.

Sang Kyung SHIN 1 ; Gonhyung KIM ; Dongwoo CHANG ; Ki Jeong NA ; Byeongwoo AHN

Affiliations

+expand

Keywords

Beagle dog; case report; tumoral calcinosis

Country

Republic of Korea

Language

Korean

Abstract

We describe a case of tumoral calcinosis in a 13-month-old female Beagle dog presenting for surgical removal of a 4x3x3 cm mass in the soft tissues of the medial right shoulder joint. On radiologic examination, the mass showed increased radiopacity. Blood analysis data indicated chronic renal failure with hyperphosphatemia and hypercalcemia. Grossly, the mass was irregular, round and multilocular, with hard consistency. Histologically, there were many variable-sized loculi surrounded by capsule and interstitial connective tissues were generated among the loculi. Inflammatory cells, fibroblasts, fibrocytes and multinucleated giant cells were present at the margins of the loculi. Most of the loculi were filled with calcium or chalky material. To our knowledge, this is the first case of tumoral calcinosis in Korea.