Since outbreak of the coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)at the end of 2019,hundreds of millions of people were infected and millions of people around the world were killed.SARS-CoV-2 is highly prone to present rapid mutations that can render vaccines ineffective.Drug therapy is currently an effective mean to prevent and treat COVID-19,and traditional Chinese medicine therapy based on clinical char-acteristics and syndrome differentiation has played an extremely important role in the prevention and treatment of COVID-19 in China.Therefore,the characteristics and mechanism of the various prescrip-tions via multiple approaches and targets used in the treatment of COVID-19,including drugs with func-tions of heat-clearing,exterior-resolving,aromatic flavor and damp-resolving,and deficiency-tonifying,based on the clinical experience of Chinese traditional medicine in preventing and treating COVID-19,in order to provide reference for the clinical treatment of such diseases with symptomatic prescriptions.