Organ Transplantation 2024;15(5):661-670

doi:10.3969/j.issn.1674-7445.2024209

Chinese practice guidelines for diagnosis and treatment of ischemic-type biliary lesion after liver transplantation

Yingcai ZHANG 1 ; Xiao FENG 1 ; Zhengran LI 1 ; Jie REN 1 ; Jin WANG 1 ; Fengping ZHENG 1 ; Wenjie CHEN 1 ; Qi ZHANG 1 ; Xiao XU 1 ; Yang YANG 1

Affiliations

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Keywords

Liver transplantation; Ischemic-type biliary lesion; Diagnosis; Treatment; Donation after brain death; Marginal donor liver; Immunosuppression; Infection

Country

China

Language

Chinese

Abstract

Over the years of exploration and development, the surgical techniques and prognosis of liver transplantation in China have been significantly improved, resulting in a notable decrease in the prevalence of postoperative complications. However, ischemic-type biliary lesion remain a non-negligible issue. The Third Affiliated Hospital of Sun Yat-sen University formulated and published the "Expert Consensus on the Diagnosis and Treatment of Ischemic-Type Biliary Lesions after Liver Transplantation in Mainland China" in 2015, which has now been updated into a guideline based on current conditions and literature reports. This guideline elaborates in detail on the definition, incidence, pathogenesis, diagnosis, prevention of high-risk factors, and treatment of ischemic-type biliary lesion, aiming to provide standardized and normative guidance for the diagnosis and treatment of ischemic-type biliary lesion after liver transplantation, thereby reducing the rate of re-transplantation and fatality, and to improve the overall quality of life of liver transplant recipients.