JOURNAL OF RARE DISEASES 2024;3(1):102-107

doi:10.12376/j.issn.2097-0501.2024.01.013

New Advances in the Use of 18F-FET PET in the Diagnosis and Management of Adult High-Grade Gliomas

Qingqing HAN 1 ; Tuo LI 1 ; Haiqun XING 1 ; Chao REN 1 ; Jiahui LIU 2 ; Yu WANG 2 ; Wenbin MA 2 ; Xin CHENG 1 ; Li HUO 3

Affiliations

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Keywords

18F-FET PET; high-grade glioma; magnetic resonance imaging; rare diseases

Country

China

Language

Chinese

Abstract

Gliomas are the most common primary intracranial tumors in adults, among which high-grade glioma patients are characterized by short survival and poor prognosis. The diagnosis, treatment, evaluation of effective treatments, and prognosis prediction of high-grade gliomas are of great significance for improving patient survival. Conventional enhanced magnetic resonance imaging has deficiencies in delineating tumor extent, identifying tumor progression and treatment-related changes. Therefore, there is a broad consensus to incorporate amino acid PET, and 18F-FET PET inparticular, into the diagnostic and therapeutic process of high-grade gliomas. In this article, we review the new research progress of 18F-FET PET in the diagnosis and treatment of adult high-grade glioma in recent years.