Korean Journal of Clinical Neurophysiology  2013;15(1):19-23

doi:10.14253/kjcn.2013.15.1.19

Leprous Neuropathy Associated with Predominant Proprioceptive Sensory Loss.

Tae Kwan YOON 1 ; Hee Young JO ; Ji Won YUK ; Jin Hong SHIN ; Dae Seong KIM

Affiliations

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Keywords

Leprosy; Proprioception; Peripheral neuropathy

Country

Republic of Korea

Language

Korean

Abstract

Some patients with leprosy may present with atypical features, such as isolated peripheral neuropathy without skin lesions, or marked proprioceptive dysfunction. We report a 56-year-old female who presented with predominant proprioceptive loss without skin lesion, but was finally confirmed as leprous neuropathy by sural nerve biopsy. It is postulated that large myelinated fibers were affected by chronic immunological reactions triggered by inactive bacterial particles, producing a peripheral neuropathy presenting as predominant proprioceptive sensory loss without typical skin lesions.